Recommendation 1.5.5 in the guideline on dementia states that treatment should be under the following conditions:
•For people who are not taking an AChE inhibitor or memantine, prescribers should only start treatment with these on the advice of a clinician who has the necessary knowledge and skills.
•Once a decision has been made to start an AChE inhibitor or memantine, the first prescription may be made in primary care.
•For people with an established diagnosis of Alzheimer's disease who are already taking an AChE inhibitor, primary care prescribers may start treatment with memantine without taking advice from a specialist clinician.
•Ensure that local arrangements for prescribing, supply and treatment review follow the NICE guideline on medicines optimisation.
•Do not stop AChE inhibitors in people with Alzheimer's disease because of disease severity alone.