According to an editorial, there remains little evidence for any recommended treatment, partly because trials of rare diseases are challenging, and in this study, both drugs were less effective than expected—ulcers healed in only 47% of the participants within 6 months. The author notes that as pyoderma gangrenosum is severe and difficult to treat, new and better treatments are clearly needed, and the data from this study provide a baseline against which all other options can be compared in future studies.