Restricted indication and new contra-indications are as follows:
• Esmya is now indicated for the:
-intermittent treatment of moderate to severe symptoms of uterine fibroids in women of reporductive age who are not eligible for surgery
- one course of pre-operative treatment of moderate to severe symptoms of uterine fibroids in adult women of reproductive age
• Esmya treatment is to be initiated and supervised by a physician experienced in the diagnosis and treatment of uterine fibroids
• Esyma is contraindicated in women with underlying liver disorders