The PRAC has recommended an update to the product information to advise on measures to minimise the risk of osteonecrosis of the jaw, and the introduction of a patient reminder card which will remind patients about the following:• the benefit of treatment of osteoporosis;• the risk of osteonecrosis of the jaw during treatment with Aclasta;• the need to highlight any dental problems to their doctors/nurses before starting treatment;• the need to ensure good dental hygiene during treatment;• the need to inform their dentist of treatment with Aclasta and to contact the doctor and dentist if problems with the mouth or teeth occur during treatment.