Anti-interleukin 1 agents for the treatment of recurrent pericarditis: a systematic review and meta-analysis

Meta-analysis (7 studies; n=397) found use of anakinra or rilonacept was associated with a reduction in pericarditis recurrences (IRR 0.06, 95% CI 0.03 to 0.14) vs placebo and/or standard medical therapy, but an increased risk of infections (RR 3.65, 95% CI 1.23 to 10.85).

Heart