Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection

RCT (n=410;France) found shorter course of 6 weeks of antibiotic therapy did not meet criterion for noninferiority vs. longer course of 12 weeks and resulted in unfavourable outcomes in a higher percentage of patients, most of whom had undergone débridement with implant retention

Source:

New England Journal of Medicine