Antibody Response After SARS-CoV-2 Infection and Implications for Immunity: A Rapid Living Review

Review (66 observational studies;n =16 525) found most adults with SARS-CoV-2 infection confirmed by RT-PCR develop detectable levels of IgM and IgG antibodies after infection with SARS-CoV-2 and IgG levels peak ~25 days after symptom onset and may remain detectable for ≥120 days

SPS commentary:

The Scientific Medical Policy Committee of the American College of Physicians developed rapid, living practice points based on this systematic review, summarising the current and best available evidence on the antibody response to SARS-CoV-2 infection, antibody durability after initial infection with SARS-CoV-2, and antibody protection against reinfection with SARS-CoV-2.

Source:

Annals of Internal Medicine

Resource links:

Rapid, living practice points