Assessment of Catheter Ablation or Antiarrhythmic Drugs for First-line Therapy of Atrial Fibrillation: A Meta-analysis of Randomized Clinical Trials

Analysis (6 RCTs;n=1212) found catheter ablation linked to reduction in atrial arrhythmias (32.3% vs 53%; risk ratio 0.62;95% CI,0.51-0.74;p <0 .001), and hospitalisations (5.6% vs 18.7%;0.32;0.19-0.53;p<0 .001) vs. antiarrhythmic drugs, with no difference in major adverse events

JAMA Cardiology