Association of CYP2C19 and CYP2D6 Poor and Intermediate Metabolizer Status With Antidepressant and Antipsychotic Exposure: A Systematic Review and Meta-analysis

Review (94 studies;n=8379) found link between CYP2C19/CYP2D6 genotype (CYPGN) and drug levels of several psychiatric drugs (risperidone, aripiprazole, haloperidol, escitalopram, sertraline) was quantified with sufficient precision to be useful as foundation for CYPGN-based dosing

JAMA Psychiatry