Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial

Open-label RCT did not support addition of azithromycin to standard of care, which included hydroxychloroquine (n=447; OR for improved clinical status at day 15=1.36; 95%CI 0.94–1.97).rates of QTc prolongation, cardiac arrest, or ventricular arrhythmias were similar between arms.


The Lancet