FDA issues Drug Safety Communication on risk of heart problems, seizures, coma, or even death with use of higher than recommended doses of diphenhydramine (Benadryl)

FDA is aware of news reports of teenagers ending up in emergency rooms or dying after participating in the “Benadryl Challenge” encouraged in videos posted on TikTok. It is investigating these reports and conducting a review to determine if additional cases have been reported.

Source:

US Food and Drug Administration