Burden of enteral supplement interactions with common antimicrobial agents: a single-centre observational analysis
This case series (4067 prescriptions for ciprofloxacin, levofloxacin or doxycycline) found 810 (19.3%) had an interacting enteral therapy (calcium or iron salt) administered within 2 hours of the antimicrobial, which may impair oral bioavailability and limit treatment efficacy.
Source:
European Journal of Hospital Pharmacy