Cancer risk in individuals with major birth defects: large Nordic population based case-control study among children, adolescents, and adults

Study (62 295 cancer cases; 724 542 controls, born between 1967 and 2014) note that the increased risk of cancer in individuals with birth defects (3.5% vs. 2.2%; OR 1.74; 99% CI, 1.63-1.84) persisted into adulthood, both for non-chromosomal and chromosomal anomalies.

British Medical Journal