Choosing Between Ketamine and Electroconvulsive Therapy for Outpatients With Treatment-Resistant Depression—Advantage Ketamine?
In viewpoint, author suggests people with treatment-resistant depression and their clinicians should consider trial of IV ketamine before ECT, while ensuring that consideration has also been made for older, evidence-based approaches and recognizing when ECT might be preferred.
Source:
JAMA Psychiatry
Resource links:
Viewpoint: Knowns, unknowns, possibilities, barriers, and opportunities
SPS commentary:
Another viewpoint claims that ketamine has the potential to change approach to the clinical management of depression if knowledge, attitudinal, and regulatory barriers can be overcome, and if risks related to comorbidities and concurrent medications are addressed by close supervision.