Cognitive performance declines in older adults with type 1 diabetes: results from 32 years of follow-up in the DCCT and EDIC Study
This analysis (n=1,051) found substantial declines in memory and psychomotor and mental efficiency, that were larger during 18-32 years of follow-up. Exposure to higher hbA1c levels, more episodes of severe hypoglycaemia and elevated BP were independent risk factors.
Source:
The Lancet Diabetes & Endocrinology
SPS commentary:
An accompanying comment notes that the present observations have important clinical implications, and that cognitive function in people with type 1 diabetes must receive greater attention. In addition to the importance of maintaining metabolic and blood pressure control, the avoidance of severe hypoglycaemia is essential to preserve cognitive function later in life.