Cost and health impacts of adherence to the National Institute for Health and Care Excellence schizophrenia guideline recommendations

Study found full adherence to guideline recommendations would decrease cost and improve QALYs. Based on NICE willingness-to-pay threshold of £20,000–£30,000/QALY gained, prompt provision of clozapine for treatment-resistant schizophrenia results in greatest net monetary benefit.

British Journal of Psychiatry