Daridorexant for treating long-term insomnia – guidance (TA922)

NICE recommends daridorexant for insomnia in adults with symptoms lasting ≥3 nights per week for ≥3 months, where daytime functioning is considerably affected, only if cognitive behavioural therapy for insomnia has been tried but not worked, or is not available or unsuitable.

SPS commentary:

NICE recommend that the length of treatment should be as short as possible. Treatment with daridorexant should be assessed within 3 months of starting and should be stopped in people whose long-term insomnia has not responded adequately. If treatment is continued, assess whether it is still working at regular intervals.

National Institute for Health and Care Excellence