Direct Healthcare Professional Communication: EYLEA 40 mg/mL (aflibercept solution for intravitreal injection): Higher risk of intraocular pressure increase with the pre-filled syringe
Cases of increased intraocular pressure have been reported more frequently (~7-fold) with pre-filled syringe compared with Luer-lock syringe of solution for injection in a vial. Correct handling of pre-filled syringe and training are key to mitigate this risk.
Source:
Bayer