DTB commentary: Is tramadol associated with an increase in all-cause mortality among patients with osteoarthritis?
Commentary is provided on cohort study which found initial prescription of tramadol linked to higher risk of mortality over 1 year of follow-up vs. commonly prescribed NSAIDs but not when compared with codeine, thus tramadol should be used with same caution as other opioids.
Source:
Drug and Therapeutics Bulletin