DTB Select: COPD—effect of metoprolol in people with no proven cardiac indication

Summary and context are provided for an RCT (n=532) which found, compared to placebo, use of metoprolol in patients with COPD did not increase the time to first exacerbation, or rate of exacerbations, but increased the risk of severe exacerbations requiring hospital admission.


Drug and Therapeutics Bulletin