Effect of Intensive Blood Pressure Lowering on Cardiovascular Outcomes: A Systematic Review Prepared for the 2020 U.S. Department of Veterans Affairs/U.S. Department of Defense Guidelines
Review of 8 systematic reviews found high-strength evidence of benefit of a 10–mm Hg reduction in systolic blood pressure for cardiovascular outcomes among patients with hypertension in the general population, patients with chronic kidney disease, and patients with heart failure.
Source:
Annals of Internal Medicine
Resource links:
US guidance for the diagnosis and management of hypertension in the primary care setting - synopsis:
SPS commentary:
Authors highlight that data were less clear for patients with diabetes mellitus or cardiovascular disease.
These findings provided the evidence base for recent US guidance for the diagnosis and management of hypertension in the primary care setting.