Effect of Long-Acting Injectable Antipsychotics vs Usual Care on Time to First Hospitalization in Early-Phase Schizophrenia: A Randomized Clinical Trial

RCT (n=489) found use of long-acting injectable aripiprazole was associated with a significant delay in time to first hospitalisation compared to usual care, (613.7 vs. 530.6 days, respectively; HR 0.56; 95% CI, 0.34- 0.92; p=0.02), with NNT to prevent 1 hospitalisation of 7.


JAMA Psychiatry