Effect of Passive Choice and Active Choice Interventions in the Electronic Health Record to Cardiologists on Statin Prescribing: A Cluster Randomized Clinical Trial

RCT (82 cardiologists, 16 practices in US, n=11 693) found neither intervention resulted in significant change in statin prescribing, but in patients with atherosclerotic CVD, active choice intervention led to a significant increase in statin prescribing at optimal dose.

SPS commentary:

In passive choice, cardiologists had to manually access an alert embedded in the EHR to select options to initiate or increase statin therapy. In active choice, an interruptive EHR alert prompted the cardiologist to accept or decline guideline-directed statin therapy.

JAMA Cardiology