Effect of Reduced-Dose vs High-Dose Glucocorticoids Added to Rituximab on Remission Induction in ANCA-Associated Vasculitis: A Randomized Clinical Trial

RCT (n=140) found reduced dose prednisolone (0.5 mg/kg/day) was non-inferior to standard dose (1mg/kg/day) when given in conjunction with rituximab, for remission at 6 months (71.0% vs 69.2% respectively, difference +1.8%, p=0.003 for non-inferiority).

Source:

Journal of the American Medical Association