Effect of Vitamin D Supplementation, Omega-3 Fatty Acid Supplementation, or a Strength-Training Exercise Program on Clinical Outcomes in Older Adults: The DO-HEALTH Randomized Clinical Trial

RCT (n=2,157) found no significant benefits in systolic and diastolic blood pressure changes, cognitive and physical performance assessment and incidence of nonvertebral fractures and infections, for vitamin D or omega-3 supplementation with or without an exercise program.

Journal of the American Medical Association