Effectiveness of a Multimedia Educational Intervention to Improve Understanding of the Risks and Benefits of Palliative Chemotherapy in Patients With Advanced Cancer: A Randomized Clinical Trial

RCT of 186 patients with advanced colorectal or pancreatic cancer found provision of an educational video and booklet did not alter patients’ expectation of cure from palliative chemotherapy and did not increase distress, despite frank prognostic information.

JAMA Oncology