Effectiveness of Sequential Chemoradiation vs Concurrent Chemoradiation or Radiation Alone in Adjuvant Treatment After Hysterectomy for Cervical Cancer - The STARS Phase 3 Randomized Clinical Trial

In this trial (n=1048), sequential chemoradiation was superior to concurrent chemoradiation (CCRT; 90.0% v 85.0%; HR 0.65; 95% CI 0.44-0.96) or radiation alone (RT; 90.0% vs 82.0%; HR 0.52; 95% CI 0.35-0.76) for 3-year disease-free survival, with no difference for CCRT versus RT.

Source:

JAMA Oncology