Effects of Proton Pump Inhibitors on Glycemic Control and Incident Diabetes: A Systematic Review and Meta-Analysis

Review of 7 studies (n=342) for glycaemic control and 5 studies (n=244,439) for risk of incident diabetes found add on PPI was associated with a significant decrease in HbA1c (−0.36 %; 95%CI, −0.68 to −0.05), but did not reduce the risk of incident diabetes.

Journal of Clinical Endocrinology and Metabolism