Efficacy and Safety of Dulaglutide 3.0 mg and 4.5 mg Versus Dulaglutide 1.5 mg in Metformin-Treated Patients With Type 2 Diabetes in a Randomized Controlled Trial (AWARD-11)

RCT in 1852 patients with type 2 diabetes inadequately controlled by metformin found dose escalation of dulaglutide from 1.5 mg to 3.0 mg or 4.5 mg once weekly provided improved glycaemic control and body weight reduction vs. 1.5 mg at 36 weeks, with a similar safety profile.

Diabetes Care