Efficacy of pitolisant in patients with high burden of narcolepsy symptoms: pooled analysis of short-term, placebo-controlled studies

Pooled analysis of 2 RCTs (n=118) found pitolisant (PT), at once-daily doses up to 35.6mg, was efficacious for reducing excessive daytime sleepiness and cataplexy. Mean sleep latency increased from 3.5 to 10.4 mins with pitolisant and 3.4 to 6.8 mins with placebo (p= 0.017).

Source:

Sleep Medicine