Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial

This RCT (n=559) of older and/or frail patients with advanced gastroesophageal cancer found reduced intensity oxaliplatin/capecitabine chemotherapy was non-inferior to the reference in terms of progression-free survival, and improved patient experience.

JAMA Oncology