Revised SPC: Cozaar-Comp (losartan with hydrochlorothiazide) film-coated tablets -

Revised SPC: Cozaar-Comp (losartan with hydrochlorothiazide) film-coated tablets
Information type: Drug prescribing
Source: electronic Medicines compendium
Specialities: Cardiovascular system disorders | Renal and urologic disorders | Skin disorders
Summary
Sections 4.4 and 4.5 now advise concomitant use of other drugs that may increase serum potassium (e.g. trimethoprim-containing products) is not recommended. Also, an increased risk of non-melanoma skin cancer with cumulative dose of hydrochlorothiazide exposure has been observed.
UKMi comment
Guidance has also been added for patients to check their skin regularly and take possible preventative measures.
Related links: