Revised SPC: Glucophage 500mg and 850mg tablets (metformin hydrochloride) -

Revised SPC: Glucophage 500mg and 850mg tablets (metformin hydrochloride)
Information type: Drug prescribing
Source: Glenmark Pharmaceuticals Europe Ltd
Specialities: Diabetes | Endocrine system disorders
Summary
Sections 4.2, 4.3 and 4.4 have been updated to include detailed advice on the use of metformin in patients with/at risk of renal impairment. The max dose in moderate impairment is 1000 mg daily, given as 2 divided doses, and it is contra-indicated in patients with CrCl <45mL/min.
UKMi comment
Please see link to the SPC for Glucophage tablets for detailed dosing and monitoring advice. Note that the SPCs for Glucophage SR and generic formulations of metformin have not been updated.
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