UK Medicines Information
Revised SPC: Rezolsta 800 mg/150 mg (darunavir/ cobicistat) film coated tablets
Information type:
Drug prescribing
Source:
electronic Medicines compendium
Specialities:
Infection and infectious diseases | Obstetrics and gynaecology
Summary
Treatment with Rezolasta during pregnancy results in low darunavir exposure; cobicistat levels decrease and may not provide sufficient boosting. Treatment should not be initiated during pregnancy; women who become pregnant during treatment should be switched to an alternative.
UKMi comment
The SPC notes that darunavir given with low dose ritonavir may be considered as an alternative.
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