Revised SPC: Tetralysal (lymecycline) 300 -

Revised SPC: Tetralysal (lymecycline) 300
Information type: Drug prescribing
Source: electronic Medicines compendium
Specialities: Infection and infectious diseases | Liver disorders | Neurological disorders | Oral and dental health | Paediatric and neonatal medicine | Renal and urologic disorders | Skin disorders
Summary
SPC now advises to take with glass of water to reduce risk of oesophageal irritation/ulceration.Concomitant use of oral retinoids should be avoided. Warnings also added about renal/hepatic impairment/hepatotoxicity/antibiotic resistance/phototoxicity and use of expired medication
UKMi comment

The SPC now warns that use of expired tetracyclines can lead to renal tubular acidosis (Pseudo-Fanconi syndrome) which is readily reversible when treatment is discontinued.
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