Pentosan polysulfate sodium for treating bladder pain syndrome

Pentosan polysulfate sodium for treating bladder pain syndrome – guidance (TA610)
Information type: Drug best practice guidance
Source: National Institute for Health and Care Excellence
Specialities: Renal and urologic disorders
Summary
NICE recommends pentosan polysulfate sodium as an option for bladder pain syndrome with glomerulations or Hunner's lesions in adults with urinary urgency and frequency, and moderate to severe pain, with set restrictions.
UKMi comment
Pentosan polysulfate sodium is only recommended if:
• The condition has not responded to an adequate trial of standard oral treatments
• It is not offered in combination with bladder instillations
• Any previous treatment with bladder instillations was not stopped because of lack of response
• It is used in secondary care
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Pentosan polysulfate sodium for treating bladder pain syndrome – guidance (TA610)