Editorial notes all medications were administered at the same time at bedtime or upon awakening, which improved compliance and there was no increase in nocturnal hypotension and potential sequelae such as falls. However, there are other considerations. Many antihypertensive drugs, particularly diuretics, may not be tolerated when given at bedtime, and in the study, diuretics were used somewhat less frequently in the bedtime administration group. Also, the study included only a Caucasian population in Spain, so further studies in multiracial groups need to be conducted before the routine bedtime intake of antihypertensive drugs can be recommended widely. In addition, the study by design could not determine the effect of bedtime vs. morning intake of antihypertensive drugs in dippers and non-dippers on cardiovascular outcomes.