Acute Kidney Injury in Patients on SGLT2 Inhibitors: A Propensity-Matched Analysis -

Acute Kidney Injury in Patients on SGLT2 Inhibitors: A Propensity-Matched Analysis
Information type: Other primary research
Source: Diabetes Care
Specialities: Diabetes | Renal and urologic disorders
Summary
Based on data from 2 cohorts of patients with type 2 diabetes (n=3168), the rate of acute kidney injury by KDIGO definition was lower in patients on SGLT2 inhibitor users compared to non-users.
UKMi comment

The U.S. Food and Drug Administration (FDA) had previously (2016) strengthened the existing warning about the risk of acute kidney injury for canagliflozin and dapagliflozin. The warnings in the drug labels include information about acute kidney injury and recommendations to minimise this risk.
Related links: Link to US FDA Drug Safety Communication