Arrhythmia risk and β-blocker therapy in pregnant women with long QT syndrome -

Arrhythmia risk and β-blocker therapy in pregnant women with long QT syndrome
Information type: Other primary research
Source: Heart
Specialities: Cardiovascular system disorders | Obstetrics and gynaecology
Summary
Japanese review of 136 pregnancies in women with long QT syndrome found 6 cardiac events during pregnancy in patients not taking beta blockers (BBs n=88) vs 0 events for those on BBs (n=38).
UKMi comment
Fetal growth rate and proportion of patients with congenital malformation were similar between the two groups, but premature delivery and low birthweight infants were more common in those taking BBs (OR 4.79, 95% CI 1.51 to 15.21 and OR 3.25, 95% CI 1.17 to 9.09, respectively).
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