Association Between Bariatric Surgery and Macrovascular Disease Outcomes in Patients With Type 2 Diabetes and Severe Obesity -

Association Between Bariatric Surgery and Macrovascular Disease Outcomes in Patients With Type 2 Diabetes and Severe Obesity
Information type: Other primary research
Source: Journal of the American Medical Association
Specialities: Cardiovascular system disorders | Diabetes | Surgery
Summary
Study (n=20,235) found that bariatric surgery was associated with a lower composite incidence of macrovascular events at 5 years vs no surgery (2.1% vs 4.3%, HR 0.60, 95%CI 0.42-0.86). Authors highlight that these findings require confirmation in randomised clinical trials.
UKMi comment
A related editorial discusses this research. For prevention of macrovascular events, the societal benefits of aggressive medical therapy for diabetic control are modest and the costs are great. Bariatric surgery has been shown to improve control of type 2 diabetes and various cardiovascular (CV) risk factors. Even though there appears to be relatively weak evidence supporting aggressive medical management of type 2 diabetes for reducing CV events and mortality, evidence for the benefits of bariatric surgery for improving these outcomes is increasing.
Related links: Editorial