BP Control and Long-Term Risk of ESRD and Mortality

This analysis (n=1,067) found that compared to usual blood pressure (bp) control strict bp control did not affect the adjusted relative risk of end stage renal disease (0.95, 95%CI 0.78-1.16) however the adjusted relative risk of death was reduced (0.81, 0.68-0.98).

This analysis of data from the African American Study of Kidney Disease, which had randomly allocated patients to strict BP control (mean arterial pressure <92 mm Hg) or usual BP control (mean arterial pressure 102-107 mm Hg).

 

This report also put together these findings with extended follow-up results from the Modification of Diet in Renal Disease study.  In meta-analysis the unadjusted relative risk for mortality for strict vs standard bp control was 0.87 (0.76-0.99), and the unadjusted relative risk of end stage renal disease was 0.88 (0.78-1.00)