Blood pressure variability and risk of cardiovascular events and death in patients with hypertension and different baseline risks -

Blood pressure variability and risk of cardiovascular events and death in patients with hypertension and different baseline risks
Information type: Other primary research
Source: European Heart Journal
Specialities: Cardiovascular system disorders
Summary
Analysis of VALUE (valsartan vs amlodipine; n=15 245) found patients in highest quintile of standard deviation (SD) had increased risk of CV events (HR 2.1; P < 0.0001). A 5 mmHg increase in SD of systolic BP was associated with a 10% increase mortality (1.10; P = 0.002).
UKMi comment
Study authors conclude that all patients with hypertension receiving blood pressure lowering treatment should be monitored carefully to achieve consistency of control, irrespective of baseline risk, particularly younger patients or those with a low mean systolic blood pressure as associations were stronger in these groups.
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