Cardiovascular event rates and mortality according to achieved systolic and diastolic blood pressure in patients with stable coronary artery disease: an international cohort study

This analysis of 22,672 patients with stable coronary artery disease followed up over 5 yrs shows systolic blood pressure of less than 120 mmHg and diastolic blood pressure of less than 70 mmHg were each associated with adverse cardiovascular outcomes (CV death, MI, or stroke).

The results of this study suggest that caution should be taken in the use of blood pressure-lowering treatment in patients with coronary artery disease.

 

An editorial discusses the findings of this study, highlighting that the results warn against an extensive extrapolation of the results of the SPRINT trial which advocated that “the lower the achieved blood pressure, the better”, should be pursued in all individuals at high cardiovascular risk.