Clopidogrel With Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) Trial: One-Year Outcomes -

Clopidogrel With Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) Trial: One-Year Outcomes
Information type: Other primary research
Source: Circulation Research
Specialities: Stroke
Summary
Follow-up of this Chinese trial (n=5170) found early benefit of clopidogrel-aspirin (CA) treatment in reducing risk of subsequent stroke persisted for duration of 1-year of follow-up (stroke occurred in 10.6% CA group, vs. 14% aspirin group; HR 0.78; 95% CI, 0.65–0.93; p=0.006).
UKMi comment
Primary analysis of the CHANCE trial had found combined treatment of clopidogrel and aspirin decreases 90-day risk of stroke without increasing haemorrhage in comparison with aspirin alone.
Related links: Primary analysis (90 days)