Population pharmacokinetics and dosing recommendations for the use of deferiprone in children younger than 6 years -

Population pharmacokinetics and dosing recommendations for the use of deferiprone in children younger than 6 years
Information type: Other primary research
Source: British Journal of Clinical Pharmacology
Specialities: Paediatric and neonatal medicine
Summary
This analysis of 18 paediatric patients concludes that a dosing regimen of 25mg/kg tds is recommended in children aged <6 years, with the possibility of titration up to 33.3mg/kg tds.
UKMi comment
Section 4.2 of the current Ferripro SPC 100 mg/ml oral solution (deferiprone) states “There are limited data available on the use of deferiprone in children between 6 and 10 years of age, and no data on deferiprone use in children under 6 years of age”.
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