Overall, 38% of survivors reported having or siring a pregnancy vs 62% of siblings (male survivors HR 0.63, 95% CI, 0.58-0.68, female survivors HR=0.82, 0.76-0.89).
A related editorial discusses the implications of this research. It highlights that this can form a basis for more accurate counselling of patients as to individual risks, and that for those at risk of infertility issues appropriate pathways should be developed for the selective use of effective fertility preserving interventions