What were the impacts of the Committee on Safety of Medicines warning and publication of the NICE guidelines on trends in child and adolescent antidepressant prescribing in primary care? A population based study -

What were the impacts of the Committee on Safety of Medicines warning and publication of the NICE guidelines on trends in child and adolescent antidepressant prescribing in primary care? A population based study
Information type: Other primary research
Source: BMJ Open
Specialities: Mental health and illness | Paediatric and neonatal medicine
Summary
Study found after CSM warning, prior trend towards increased prescribing rates for SSRIs in children was significantly reversed (p<0.001)). However, after publication of NICE guidelines, prior trend towards increased prescribing resumed for those SSRIs in guidance (p<0.001).
UKMi comment
The researchers suggest it may be that the NICE guidelines inadvertently encouraged further antidepressant prescribing, at least for those SSRIs cited (fluoxetine, citalopram and sertraline) due to practitioners interpreting these recommendations as endorsing their use in young people with depression and related conditions.
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