UK Medicines Information
Activity, safety, and feasibility of cidofovir and imiquimod for treatment of vulval intraepithelial neoplasia (RT3VIN): a multicentre, open-label, randomised, phase 2 trial
Information type:
Randomised controlled trials
Source:
The Lancet Oncology
Specialities:
Cancers
Summary
This phase II study (n=180) found that cidofovir and imiquimod are equally effective alternatives to the current standard, surgery, in patients with vulval intraepithelial neoplasia after exclusion of occult invasive disease. Further phase III investigation is required.
UKMi comment
A related commentary discusses these study findings.
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Comment