Effect of Cognitive Therapy With Antidepressant Medications vs Antidepressants Alone on the Rate of Recovery in Major Depressive Disorder -

Effect of Cognitive Therapy With Antidepressant Medications vs Antidepressants Alone on the Rate of Recovery in Major Depressive Disorder
Information type: Randomised controlled trials
Source: JAMA Psychiatry
Specialities: Mental health and illness
Summary
Study in 452 outpatients found that cognitive therapy combined with antidepressant treatment enhances rates of recovery from major depressive disorder vs. antidepressants alone (72.6% vs. 62.5%, p=0.01; NNT 10), with effect limited to patients with severe, non-chronic depression.
UKMi comment
An accompanying editorial discusses the findings, and calls for better treatment options for those who do not remit with conventional antidepressant strategies, as well as the need to develop and test alternative models of psychotherapy.
Related links: Editorial