Effect of Ticagrelor Plus Aspirin, Ticagrelor Alone, or Aspirin Alone on Saphenous Vein Graft Patency 1 Year After Coronary Artery Bypass Grafting: A Randomized Clinical Trial -

Effect of Ticagrelor Plus Aspirin, Ticagrelor Alone, or Aspirin Alone on Saphenous Vein Graft Patency 1 Year After Coronary Artery Bypass Grafting: A Randomized Clinical Trial
Information type: Randomised controlled trials
Source: Journal of the American Medical Association
Specialities: Cardiovascular system disorders | Surgery
Summary
RCT (n=500) showed among patients undergoing elective CABG with saphenous vein grafting, ticagrelor + aspirin significantly increased graft patency rate after 1 year (88.7%) vs aspirin alone (76.5%); difference 12.2%, p<0.001.
UKMi comment

There was no significant difference between ticagrelor alone and aspirin alone. Further research with more patients is needed to assess comparative bleeding risks.
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